Lorentz Center - Transgenes Going Wild? Risk Assessment of Transgene Introgression from Crops into Wild Relatives from 11 Jul 2011 through 15 Jul 2011
  Current Workshop  |   Overview   Back  |   Home   |   Search   |     

    Transgenes Going Wild? Risk Assessment of Transgene Introgression from Crops into Wild Relatives
    from 11 Jul 2011 through 15 Jul 2011

 

Preliminary Program

Registration: 3rd floor Oort Building (participants’ offices and common room)

Lectures: are in room 201 of the Huygens building (connecting corridor, follow footprints on the floor)

 

Keynote lecture: 40 minutes + 15 minutes discussion (general)

Lecture: 30 minutes + 10 minutes discussion (more specific/detailed topic)

 

Lunch: is in the Gorlaeus Restaurant. The restaurant is open until 13:30hrs but we advise to come no later than 12:45hrs after that time choice is very limited. Tables for are reserved for you in the back of the restaurant.

 

Keynote lectures by invited speakers will generally introduce what we know and what we do need to know. Lectures of case studies with different model species will follow the keynote lectures to discuss recent findings. We will discuss what we can learn from these studies in the context of transgene introgression risk assessment and regulations concerned. The main program will be finished in four days. However, we plan to summarize the workshop with a scientific paper. People who would like to be involved as coauthors will stay for the fifth day to discuss and work on it. All other participants would be thanked in the acknowledgments of the paper.

 

---------------------------------------------------------------------------------------------------------------

Monday 11 July 2011

---------------------------------------------------------------------------------------------------------------

 

09:00 - 10:00          Registration, office assignment and coffee & tea

 

10:00 - 10:15          Welcome by the Lorentz Center manager Mieke Schutte

10:15 - 10:20          Welcome by Scientific Organizers

 

Introduction: Main questions for regulation and risk assessment frameworks: What regulators want from scientists? The current status and the future of genetically modified crops: chances & risks

 

Moderator: Bao-Rong Lu

10:20 - 10:55          Detlef Bartsch (keynote lecture): Transgenes going wild?

                                 Setting the scene from basic research to regulatory

                                 requirements

10:55 - 11:10          Discussions

11:10 - 11:45           Alan McHughen (keynote lecture): An international trade

                                 regulatory nightmare: Transgenes in agricultural crop

                                 commodities

11:45 - 12:00          Discussion

 

12:05-13:30            Lunchbreak @ Gorlaeus Restaurant and free discussions

                                 It is time to meet each other and discuss interested topics

 

Moderator: Geert de Snoo

13:30 - 14:10          Henk Schouten (keynote lecture): Cisgenesis in apple;

                                 breeding approach, biosafety, consumers, and regulation

14:10 - 14:25          Discussions

14:25 - 15:05          Klaas Vrieling (keynote lecture): Measuring introgression

                                 using new molecular techniques

15:05 - 15:20          Discussions

15:20 - 15:50          Coffee & tea break in the common room

15:50 - 16:20          Boet Glandorf: Regulatory aspects of the environmental

                                 risk assessment of outcrossing and introgression of GM traits

16:20 - 16:30          Discussions

 

16:30                       Wine & cheese party in the common room

 

---------------------------------------------------------------------------------------------------------------

Tuesday 12 July 2011

---------------------------------------------------------------------------------------------------------------

 

About crop-to-wild introgression, what do we know and what do we need to know? How often has crop-to-wild introgression occurred in the past? How to estimate the frequency and timing of past introgression events in wild populations? How to estimate introgression chances of transgenes?

 

Moderator: Peter H. van Tienderen

09:00 - 09:40          Normann C. Ellstrand (keynote lecture): Over a Decade of

                                 Crop Transgenes Gone Wild

09:40 - 09:55          Discussions

09:55 - 10:35          Neal Stewart jr. (keynote lecture): Transgene introgression in

                                 crop relatives: molecular evidence and mitigation strategies

10:35 - 10:50          Discussions

10:50 - 11:20          Coffee & tea break in the common room

11:20 - 11:50           Jared L. Strasburg (lecture): Estimating Short-Term and

                                 Long-Term Levels of Gene Flow

11:50 - 12:00          Discussions

 

12:00 - 14:00          Lunchbreak @ Gorlaeus Restaurant and free discussions

 

Moderator: Norman C. Ellstrand

14:00 - 14:30          Jun Rong (lecture): How to estimate the chance of transgene

                                 introgression: a carrot case study

14:30 - 14:40          Discussions

14:40 - 15:10          Tom J. de Jong (lecture): Is there ancient and recent gene

                                 flow from oilseed rape to wild populations of Brassica rapa in

                                 western Europe?

15:10 - 15:20          Discussions

15:20 - 15:50          Coffee & tea break in the common room

 

Moderators Tom de Jong and Jun Rong

15:50 - 17:30          Group discussion:

It will begin with a short introduction about the questions. Then participants will be divided into 4 groups with maximum 10 people per group. Each group will discuss the title questions as well as relevant key issues. Each group discussion will be moderated by 1 discussion leader and 1 assistant making minute. Questions are going to be collected via email and online group (e.g. Google group). In addition to the title questions, some initial questions are: what is the validity of evidence for introgression from domestic species to the wild populations, if introgression does occur can we estimate how long ago the hybridization events took place, can we predict the changes of allele frequencies in wild populations, how do we know if an allele is going to be fixed, and what can we learn from past introgression in the context of transgene introgression risk assessment? The discussions can continue and main conclusions will be summarized by discussion leaders and assistants. Dr. de Jong and Rong will be responsible for collecting comments from them.

 

---------------------------------------------------------------------------------------------------------------

Wednesday 13 July 2011

---------------------------------------------------------------------------------------------------------------

 

How to assess long-term fitness effects of transgenes in wild populations? What are some differences and similarities between the fitness effects of transgenic versus non-transgenic traits?

 

Moderator: Elze Hesse  

09:00 - 09:40          Allison A. Snow (keynote lecture): Fitness effects of

                                 transgenes in wild populations: expectations, methods, and

                                 interpretation

09:40 - 09:55          Discussions

09:55 - 10:35          Rosemary Hails (keynote lecture): What information is

                                 requested for assessing the potential of GM plants for their

                                 persistence and invasiveness?”

10:35 - 10:50          Discussions

10:50 - 11:20          Coffee & tea break in the common room

11:20 - 11:50           Bao-Rong Lu (lecture): Potential Ecological Impacts Caused

                                 By Transgene Flow To Weedy Rice: A Case Study Of

                                 Insect-Resistant Traits

11:50 - 12:00          Discussions

 

12:00 - 14:00          Lunchbreak @ Gorlaeus Restaurant and free discussions

 

Moderator: Allison A. Snow  

14:00 - 14:30          Peter H. van Tienderen (lecture): Hitchhiking of transgenes

                                  from crop to wild relatives due to selection on crop

                                 (domestication) genes

14:30 - 14:40          Discussions

14:40 - 15:10          Elze Hesse (lecture): Which plant characters influence

                                 Brassica population persistence?

15:10 - 15:20          Discussions

15:20 - 15:50          Coffee & tea break in the common room      

 

Moderators: Cilia Grebenstein and Elze Hesse

15:50 - 17:30          Group discussions

In addition to the title questions, some initial questions are: How can fitness effects of transgenes be estimated especially when we can not put them in the field or we can only conduct small-scale experiments? Do spatial- and temporal scales matter? What is the role of genotype and environment interaction? Dr. Hesse and Grebenstein will be responsible for collecting comments.

 

17:30 - 18:00          Transfer by bus to party boat Olympia

18:00 - 22:00          Workshop dinner on the boat @ Groene Hart cruises

                                 Sign up here. For menu and more information click here

 

---------------------------------------------------------------------------------------------------------------

Thursday 14 July 2011

---------------------------------------------------------------------------------------------------------------

 

How to predict the risk of transgene introgression? For regulations and risk assessment frameworks, what suggestions should we make?

 

Moderator: Atiyo Ghosh

09:00 - 09:40          Danny Hooftman (keynote lecture) : Extrapolating empirical

                                 resulst in time and space: modelling tool boxes for predicting

                                 introgression of transgenes

09:40 - 09:55          Discussions

09:55 - 10:35          Patsy Haccou (keynote lecture) : The consequences of

                                 repetition and randomness: hazard rates of introgression.

10:35 - 10:50          Discussions

10:50 - 11:20          Coffee & tea break in the common room

11:20 - 11:50           Patrick G. Meirmans (lecture): Modelling the chromosome-

                                 wide consequences of transgene introgression

11:50 - 12:00          Discussions

 

12:00 - 14:00          Lunchbreak @ Gorlaeus Restaurant and free discussions

 

Moderators: Atiyo Ghosh and Patsy Haccou

14:00 - 15:30          Group discussions

In addition to the title questions, some initial questions are: What are the possible unwanted consequences of transgene introgression? There are two aspects of risk: incidence (the probability an event occurs) and consequence (the impact of an event should it occur). How can these two aspects be combined to predict the risk for effective policy making? Dr. Haccou and Ghosh will be responsible for collecting comments.

 

15:30 - 16:00          Coffee & tea break 

16:00 - 16:15          Take home message and farewell to participants who would

                                 like to leave today

 

 

---------------------------------------------------------------------------------------------------------------

Friday 15 July 2011

---------------------------------------------------------------------------------------------------------------

 

 

Moderator: Tom de Jong

09:00 - 10:30          Discuss the main structure and contents of the paper and the

                                 contributions of co-authors (divide co-authors into subgroups)  

10:30 - 11:00          Coffee & tea break in the common room

11:00 - 12:00          Discuss the detail content of the paper (in different subgroups

                                 of co-authors)

 

12:00 - 14:00          Lunchbreak @ Gorlaeus Restaurant and free discussions

 

Moderator: Klaas Vrieling

14:00 - 14:15          Summary talk about how to detect introgression and the

                                 evidence of past introgression from crops into wild relatives

                                 (de Jong)

14:15 - 14:30          Discussions

14:30 - 14:45          Summary talk about how to assess fitness effects (transgenic

                                 versus non-transgenic traits) (Hesse)

14:45 - 15:00          Discussions

15:00 - 15:15          Summary talk about mathematical and statistical tools for

                                 predicting the risks of transgene introgression (Haccou)

15:15 - 16:00          Discussions

16:00 - 16:30          Coffee & tea break in the common room and farewell

 

 

 

===end of workshop===

 



   [Back]